Reviewed September 3, 2026 by the LabWalkIns Editorial Team

PSA Test: Prostate-Specific Antigen Screening

PSA is a protein produced by the prostate gland, and the PSA blood test is used to screen for prostate cancer and to monitor known prostate conditions. PSA can also rise with benign prostate enlargement, infection, or recent procedures, so an elevated result does not by itself mean cancer. Screening decisions involve a discussion of benefits and harms with a clinician, and results over time are often more informative than a single value. Further evaluation may include a repeat test or imaging.

Key Takeaways

  • PSA is a protein produced by the prostate gland.
  • The PSA blood test is used to screen for prostate cancer and to monitor known prostate conditions.
  • PSA can also rise with benign prostate enlargement, infection, or recent procedures.
  • Screening decisions involve a discussion of benefits and harms with a clinician.
  • An elevated PSA does not by itself mean cancer; further evaluation may be needed.
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Frequently Asked Questions

What is a normal PSA level?

There is no single normal cutoff. Many clinicians use age-specific reference ranges, and trends over time matter. Discuss your result with a clinician.

Can I order a PSA test without a doctor?

PSA testing is available through some direct-access menus. Because interpretation requires context, discuss results with a clinician.

What can cause a high PSA?

Prostate cancer, benign enlargement, prostatitis, and recent ejaculation or procedures can raise PSA.

Do I need to fast for a PSA test?

Fasting is not required for a PSA test.

Sources

Reviewed by the LabWalkIns Editorial Team

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